The Merseyside derby was cleared to take place at Everton’s Goodison Park Stadium, while Liverpool can play home games at Anfield when the Premier League season restarts.
The June 21 game could be the first opportunity for the Reds, who have a 25-point lead at the top, to clinch the title.
It was one of the games considered risky due to fear that fans might congregate off the field.
St Mary’s of Southampton had been designated as a possible neutral location.
But Liverpool’s ground safety advisory group has now recommended that both Everton and Liverpool be able to play their remaining home accessories “safely” behind closed doors in their stadiums.
“We are confident that the supporters of these two great clubs will abide by safety advice to avoid visiting stadiums where matches are played at home and away,” said a joint statement by Blue Union and Spirit of Shankly, supporters groups from Everton and Liverpool. , respectively.
“We fully understand the importance of the blockade as a measure to control Covid-19 and we would encourage fans to stay away from any stadium and avoid congregating in numbers.”
Liverpool can win their first league title in 30 years by beating Everton if second-placed Manchester City lose at home to Arsenal on June 17.
The 2019-20 season has been suspended since March due to the coronavirus pandemic.
The group that made the decision was chaired by Deputy Mayor and Councilor Wendy Simon and included representatives from the police, fire service and fan groups from both clubs.
The corresponding licensing committee is now expected to issue a security certificate.
“Many factors have been taken into account, especially the safety of the players, match officials and staff present,” said Simon.
“We are confident that the measures in force will allow the matches to be held behind closed doors without any detrimental impact for all concerned and we recommend to the council that the safety certificates for both areas be modified to allow this to happen.”
Merseyside police had previously said they had “no objection” to the game being played at Goodison, while Liverpool Mayor Joe Anderson reversed his initial opposition.
Everton v Liverpool will be one of 25 Premier League games that Sky Sports will stream for free.
The remaining 92 matches will be shown live on Sky Sports, BT Sport, BBC Sport or Amazon Prime.